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Randomized Trial of Standard Methadone Treatment Compared to Initiating Methadone without Counseling: 12-month Findings

ABSTRACT

Aims:  This study aimed to determine the relative effectiveness of 12-months of Interim Methadone (IM; supervised methadone with emergency counseling only for the first 4 months of treatment), Standard Methadone treatment (SM; with routine counseling) and Restored Methadone treatment (RM: routine counseling with smaller caseloads).

Design:  A randomized controlled trial was conducted comparing: IM, SM, and RM treatment. IM lasted for 4 months after which participants were transferred to SM.

Setting:  The study was conducted in two methadone treatment programs in Baltimore, MD, USA.

Participants:  The study included 230 adult methadone patients newly-admitted through waiting lists.

Measurements:  We administered the Addiction Severity Index and a supplemental questionnaire at baseline, 4-, and 12-months post- baseline.

Measurements included retention in treatment, self-reported days of heroin and cocaine use, criminal behavior and arrests, and urine tests for heroin and cocaine metabolites.

Findings:  At 12 months, on an intent-to-treat basis, there were no significant differences in retention in treatment among the IM, SM and RM groups (60.6%, 54.8% and 37.8%, respectively). Positive urine tests for the three groups declined significantly from baseline (ps < 0.001 and 0.003, for heroin and cocaine metabolistes respectively) but there were no significant Group x Time interactions for these measures. Thirty-one percent of the sample reported at least one arrest during the year, but there were no significant between-group effects.

Conclusions:  Limited availability of drug counseling services should not be a barrier to providing supervised methadone to adults dependent on heroin – at least for the first 4 months of treatment.

Posted in: Journal Article Abstracts on 10/26/2011 | Link to this post on IFP |
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