Globalization has significant implications for the professions, with the societies and the regulators around them changing and the realities of professional work in large organizations taking on increasingly transnational dimensions. However, while there is no lack of empirical studies of the globalization of individual professions and firms, the implications of processes of globalization, reregulation and governmental rescaling for neo-Weberian sociologies of the professions has not received the same attention. This article seeks to rectify this gap in knowledge by developing a transnational neo-Weberian sociology of the professions that takes account of the rescaling of the world that the professions inhabit and the important new research questions generated about the multi-scalar influences on the forms of regulation, power and legitimacy that underlie professional projects.