Abstract
Magnetic resonance imaging (MRI) has been used to analyze highly specific volumetric and morphological features of the brains
of individuals with autism spectrum disorder (ASD). To date, there are few comprehensive studies examining the prevalence
of neuroradiologic findings seen on routine MRI scans in children with ASD. This study examined the prevalence of neuroradiologic
findings in children with high functioning ASD, and compared these rates to those in children with Attention-Deficit/Hyperactivity
Disorder (ADHD) and children who are typically developing (TD). Results showed that approximately 90% of children had normal
MRI scans. There was no significant effect of diagnosis on the total number of neuroradiological findings or the number of
specific brain findings. Implications and future research directions are discussed.
of individuals with autism spectrum disorder (ASD). To date, there are few comprehensive studies examining the prevalence
of neuroradiologic findings seen on routine MRI scans in children with ASD. This study examined the prevalence of neuroradiologic
findings in children with high functioning ASD, and compared these rates to those in children with Attention-Deficit/Hyperactivity
Disorder (ADHD) and children who are typically developing (TD). Results showed that approximately 90% of children had normal
MRI scans. There was no significant effect of diagnosis on the total number of neuroradiological findings or the number of
specific brain findings. Implications and future research directions are discussed.
- Content Type Journal Article
- Category Original Paper
- Pages 1-9
- DOI 10.1007/s10803-011-1407-6
- Authors
- Roma A. Vasa, Laboratory of Neurocognitive and Imaging Research, Center for Autism and Related Disorders, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, 3901 Greenspring Avenue, Baltimore, MD 21211, USA
- Marin Ranta, Kennedy Krieger Institute, Baltimore, MD, USA
- Thierry A. G. M. Huisman, Division of Pediatric Radiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Johns Hopkins University School of Medicine, Baltimore, MD, USA
- Pedro S. Pinto, Division of Pediatric Radiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD, USA
- Rachael M. Tillman, Kennedy Krieger Institute, Baltimore, MD, USA
- Stewart H. Mostofsky, Laboratory of Neurocognitive and Imaging Research, Center for Autism and Related Disorders, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, 3901 Greenspring Avenue, Baltimore, MD 21211, USA
- Journal Journal of Autism and Developmental Disorders
- Online ISSN 1573-3432
- Print ISSN 0162-3257